Antifertility Effect of the Ethanol Extract of Centella asiatica L. Urban Against the White Rat (Rattus norvegicus L.) in the Early Post-Implantation

Akbar, BudhidanSusilo, SusilodanRanti An Nissa, RantidanRosi Feirina Ritonga, RosidanSuci Lestari, SucidanYuni Astuti, YunidanParwito, Parwito Antifertility Effect of the Ethanol Extract of Centella asiatica L. Urban Against the White Rat (Rattus norvegicus L.) in the Early Post-Implantation. Antifertility Effect of the Ethanol Extract of Centella asiatica L. Urban Against the White Rat (Rattus norvegicus L.) in the Early Post-Implantation.

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Abstract

Centella asiatica is commonly known as centella or pegagan is one of the biological resources that have many benefits for mankind. Clinical and pharmacological study of Centella asiatica has been widely proven by scientists of the world, but there are a few properties that require further investigation in particular its effect on fertility. This research aims to know the influence of the ethanol extract of pegagan (Centella asiatica) towards the birth rates or fertility in the early post-implantation. On the research, white rat (Rattus norvegicus L.) is used as animal tested. The method that used in this research was an experiment by using randomly complete design. The tested animals were grouped into 4 treatment i.e. group I (control group), group II (dose 175 mg/kg body weight), group III (a dose of 200 mg/kg body weight) and Group IV (dose 225 mg/kg body weight). The tested animals were given the exraction of Centella asiatica leaf orally with different doses for 15 days after post-implantation. The value of post-implantation death percentage is calculated by counting the number of implantation, either containing a live fetus, or dead fetus and embryo resorb. The results showed that Centella asiatica gave the influ-ence on white white rat ferlitisation. On the grup IV treatment with the dose of 225 mg/kg body weight showed the highest KPI val-ue i.e. 57.23%.

Item Type: Article
Subjects: Fakultas Keguruan dan Ilmu Pendidikan
Fakultas Keguruan dan Ilmu Pendidikan > Pendidikan Biologi
Divisions: Fakultas Keguruan & Ilmu Pendidikan > Pendidikan Biologi
Depositing User: Furqon FFS
Date Deposited: 12 Feb 2020 04:48
Last Modified: 12 Feb 2020 04:48
URI: http://repository.uhamka.ac.id/id/eprint/904

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