IN VITRO CYTOTOXICITY ASSAY OF ETHYL ACETATE AND DIETHYL ETHER FRACTION OF BREADFRUIT LEAVES METHANOL EXTRACT ON HeLa CELL LINE

Irma Rachmaniar, Irma and Rahayu Gusti Kurniawan, Rahayu and Rini Prastiwi, Rini IN VITRO CYTOTOXICITY ASSAY OF ETHYL ACETATE AND DIETHYL ETHER FRACTION OF BREADFRUIT LEAVES METHANOL EXTRACT ON HeLa CELL LINE. In: METABOLIC SYNDROME: NOW AND FUTURE TREND. FAKULTAS FARMASI DAN SAIN UHAMKA.

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Abstract

One of the traditional medicine that can be used to cure cancer is Artocarpus altilis (Parkinson) Fosberg. Based on that fact, this study conducted to determine the in vitro cytotoxic effects of ethyl acetate fraction and diethyl ether fraction of methanol extract of breadfruit leaves on HeLa cells using MTT assay method obtained LC50. The results showed that the LC50 values of ethyl acetate fraction was 119.5363 μg/ml, while the fraction diethyl ether LC50 values was 53.8022 μg/mL. It can be concluded that both fractions potential as anticancer because the range of the LC50 under 1000 μg/ml, and diethyl ether fraction cytotoxic activity higher than ethyl acetate fractions.

Item Type: Book Section
Subjects: R Medicine > R Medicine (General)
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: Furqon furqon furqon
Date Deposited: 16 Jul 2019 03:16
Last Modified: 16 Jul 2019 03:16
URI: http://repository.uhamka.ac.id/id/eprint/709

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